DSM 74 ( DSM74 )

产品货号. M16464 CAS No. 898743-92-5

A potent, orally active PfDHODH inhibitor (IC50=0.3 uM) with antimalarial activity.

纯度: >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

规格	价格/人民币	库存	数量
5MG	￥7857	有现货
50MG	￥16038	有现货
100MG	￥20250	有现货
200MG	获取报价	有现货
500MG	获取报价	有现货
1G	获取报价	有现货

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生物学信息

产品名称

DSM 74
注意事项

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
产品简述

A potent, orally active PfDHODH inhibitor (IC50=0.3 uM) with antimalarial activity.
产品描述

A potent, orally active PfDHODH inhibitor (IC50=0.3 uM) with antimalarial activity; shows good plasma exposure in mice and is equally potent against PfDHODH and PbDHODH; suppresses growth of P. berghei in mice after oral administration.
同义词

DSM74
通路

GPCR/G Protein
靶点

Antibacterial
受体

Antibacterial
研究领域

——
适应症

——

化学信息

CAS Number

898743-92-5
分子量

293.25
分子式

C13H10F3N5
纯度

>98% (HPLC)
溶解度

——
SMILES

FC(C1=CC=C(NC2=CC(C)=NC3=NC=NN23)C=C1)(F)F
化学全称

5-methyl-N-[4-(trifluoromethyl)phenyl][1,2,4]triazolo[1,5-a]pyrimidin-7-amine

运输与储存

储存条件

(-20℃)
运输条件

With Ice Pack
稳定性

≥ 2 years

参考文献

1. Lukens AK, e tal. Proc Natl Acad Sci U S A. 2014 Jan 14;111(2):799-804.
2. Gujjar R, et al. J Med Chem. 2009 Apr 9;52(7):1864-72.
3. Lee JJ, et al. urr Microbiol. 2014 Sep;69(3):286-91.

计算器

浓度计算器

摩尔计算器

分子量计算器

产品手册

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