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DSM 74

CAS No. 898743-92-5

DSM 74 ( DSM74 )

产品货号. M16464 CAS No. 898743-92-5

A potent, orally active PfDHODH inhibitor (IC50=0.3 uM) with antimalarial activity.

纯度: >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
规格 价格/人民币 库存 数量
5MG ¥7857 有现货
50MG ¥16038 有现货
100MG ¥20250 有现货
200MG 获取报价 有现货
500MG 获取报价 有现货
1G 获取报价 有现货

生物学信息

  • 产品名称
    DSM 74
  • 注意事项
    本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
  • 产品简述
    A potent, orally active PfDHODH inhibitor (IC50=0.3 uM) with antimalarial activity.
  • 产品描述
    A potent, orally active PfDHODH inhibitor (IC50=0.3 uM) with antimalarial activity; shows good plasma exposure in mice and is equally potent against PfDHODH and PbDHODH; suppresses growth of P. berghei in mice after oral administration.
  • 同义词
    DSM74
  • 通路
    GPCR/G Protein
  • 靶点
    Antibacterial
  • 受体
    Antibacterial
  • 研究领域
    ——
  • 适应症
    ——

化学信息

  • CAS Number
    898743-92-5
  • 分子量
    293.25
  • 分子式
    C13H10F3N5
  • 纯度
    >98% (HPLC)
  • 溶解度
    ——
  • SMILES
    FC(C1=CC=C(NC2=CC(C)=NC3=NC=NN23)C=C1)(F)F
  • 化学全称
    5-methyl-N-[4-(trifluoromethyl)phenyl][1,2,4]triazolo[1,5-a]pyrimidin-7-amine

运输与储存

  • 储存条件
    (-20℃)
  • 运输条件
    With Ice Pack
  • 稳定性
    ≥ 2 years

参考文献

1. Lukens AK, e tal. Proc Natl Acad Sci U S A. 2014 Jan 14;111(2):799-804.
2. Gujjar R, et al. J Med Chem. 2009 Apr 9;52(7):1864-72.
3. Lee JJ, et al. urr Microbiol. 2014 Sep;69(3):286-91.
产品手册
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